Thermo Fisher Scientific TRPC3 Polyclonal Antibody
TRPC3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합. Lyophilized 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
| Immunocytochemistry (ICC/IF) | 1:500 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide HKLSEKLNPSVLRC, corresponding to amino acid residues 822–835 of mouse TRPC3 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736731 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the canonical TRP (TRPC) family.
The seven members of this family share activation through PLC-coupled receptors and are suggested to be components of receptor-regulated cation channels in different cell types.
Members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, indicating a possible mechanism of activation via PLC-coupled receptors.
TRPC3 encodes a Ca²⁺-permeant channel that is agonist-activated but not store-operated or directly receptor-activated.
TRPC3 physically interacts with TRPC6 and TRPC7 to form functional tetrameric channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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