Thermo Fisher Scientific RPC2 Polyclonal Antibody
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Western blot, IHC, IP 등 다양한 응용에 적합한 Rabbit Polyclonal 항체. Human POLR3B 단백질(1083-1133 aa)을 면역원으로 제작. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1083 and 1133 of Human RNA polymerase III subunit C2 (POLR3B, UniProt ID: Q9NW08-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
Target Information
POLR3B (RNA Polymerase III Subunit B) is a protein-coding gene.
Diseases associated with POLR3B include:
- Leukodystrophy, Hypomyelinating, 8 (with or without Oligodontia and/or Hypogonadotropic Hypogonadism)
- Cerebellar Hypoplasia with Endosteal Sclerosis
Related pathways:
- RNA Polymerase II Transcription Initiation and Promoter Clearance
- ATP/ITP Metabolism
Gene Ontology (GO) annotations include:
- DNA-directed 5'-3' RNA polymerase activity
- Ribonucleoside binding
An important paralog of this gene is POLR2B.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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