Thermo Fisher Scientific TRIM25 Polyclonal Antibody
TRIM25 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. 사람 유래 TRIM25(75–125 aa) 영역을 면역원으로 제작되었으며, 비결합(Unconjugated) 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TRIM25 Polyclonal Antibody
Applications
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of Human tripartite motif-containing 25 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
TRIM25, also known as estrogen responsive finger protein (EFP), is a member of the RING finger-B box-coiled coil family and a downstream target of estrogen receptor α. Mice lacking this gene show an underdeveloped uterus and reduced estrogen responsiveness, indicating its essential role in estrogen-dependent proliferation. TRIM25 expression is elevated in breast carcinoma, promoting tumor growth by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3σ. Additionally, TRIM25 E3 ubiquitin ligase activity is critical for the RIG-I signaling pathway involved in antiviral innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.