Thermo Fisher Scientific Cdc42GAP Polyclonal Antibody
Rabbit 유래 폴리클로날 Cdc42GAP 항체로 Western blot, IHC, IP 등 다양한 응용 가능. 인간 CDC42 GTPase-activating protein의 1-50번 잔기 영역을 면역원으로 사용. 액상 형태, 0.20 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Cdc42GAP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human CDC42 GTPase-activating protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
Target Information
The p190 RhoGAP protein is associated with p120 RasGAP in growth-factor stimulated and tyrosine kinase transformed cells. It functions as a GTPase-activating protein (GAP) for Rho and Rac family proteins, which are involved in cytoskeletal actin regulation and membrane ruffling.
This antibody may couple signal transduction via Ras and Rho through its association with RasGAP. The presence of two adjacent SH2 domains in the p21 RAS GAP suggests direct interaction with tyrosine kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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