Thermo Fisher Scientific SMPD1 Monoclonal Antibody (OTI3H7), TrueMAB
SMPD1 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI3H7). Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, PBS/BSA/glycerol buffer에 보관. 연구용으로 Niemann-Pick 질환 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 62–341 of human SMPD1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the SMPD1 gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. This protein also exhibits phospholipase C activity.
Defects in this gene are associated with Niemann-Pick disease type A (NPA) and type B (NPB).
Three transcript variants encoding two different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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