Thermo Fisher Scientific TRPM7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

4-6 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues C-TKESESTNSVRLML, from the C-terminus of TRPM7 (aa 1852-1865). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRPM7,uniProtId:Q96QT4-1,ncbiNodeId:9606,antigenRange:1852-1865,antigenLength:1865,antigenImageFileName:PA1-9127_TRPM7_Q96QT4-1_Goat.svg,antigenImageFileNamePDP:PA1-9127_TRPM7_Q96QT4-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_10974329

Product Specific Information

This antibody is predicted to react with canine, human and porcine based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.

Target Information

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.