Thermo Fisher Scientific RAMP3 Polyclonal Antibody
RAMP3 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간 시료에 반응합니다. IHC(P)에서 1:50~1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 버퍼(40% glycerol) 보존액에 담겨 있으며, -20°C에서 보관합니다.
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Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to a region derived from internal residues of human receptor (G protein-coupled) activity modifying protein 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635707 |
Product Specific Information
This antibody detects endogenous levels of total RAMP3 protein.
Target Information
The protein encoded by this gene belongs to the RAMP family of single-transmembrane-domain proteins, known as receptor (calcitonin) activity modifying proteins (RAMPs). These are type I transmembrane proteins with an extracellular N-terminus and a cytoplasmic C-terminus.
RAMPs are essential for transporting calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can act as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which RAMP family members are expressed.
In the presence of RAMP3, CRLR functions as an adrenomedullin receptor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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