Thermo Fisher Scientific Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) Monoclonal Antibody (CALD1/820)
Caldesmon 단백질을 표적하는 고특이적 단클론 항체로, 평활근 세포 마커로 사용됩니다. Western blot 및 면역조직화학(IHC) 분석에 적합하며, 인간 시료에 반응합니다. 단백질 A/G 정제, 액상 형태로 제공되며 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 0.25–0.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CALD1/820 |
| Immunogen | Recombinant full-length human CALD1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Does not react with Rat.
Target Information
Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon have been identified, differing in electrophoretic mobility and cellular distribution.
The h-caldesmon variant (120–150 kDa) is predominantly expressed in smooth muscle, whereas l-caldesmon (70–80 kDa) is found in non-muscle tissues and cells. Neither variant is detected in skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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