Thermo Fisher Scientific Thrombomodulin Polyclonal Antibody
Thrombomodulin 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, IP 등 다양한 실험에 적합합니다. Human 반응성, 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공되며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 512–575 of Thrombomodulin (Uniprot ID: P07204) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at −20°C and avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152826 |
Product Specific Information
- Recommended positive control: THP-1
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Thrombomodulin (TM), also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112, contains six repeated domains homologous with epidermal growth factor (EGF) and an amino-terminal domain homologous to lectin-like protein.
TM accelerates activation of protein C, contributing to thrombo-resistance and reducing clot formation on endothelial surfaces.
Immunohistochemical staining of formalin-fixed tissue for TM has been applied in studies of vascular tumors, meningiomas, and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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