Thermo Fisher Scientific Interferon alpha-2 Polyclonal Antibody
Human IFN alpha-2를 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA521926
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide containing a sequence corresponding to a region within amino acids 125–188 of interferon alpha-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_11153091 |
Product Specific Information
- Recommended positive controls: A431, H1299, HeLa, HepG2
- Predicted reactivity: Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Interferon alpha (IFN-α) is a Type I interferon belonging to a family of structurally related, species-specific proteins found in vertebrates. Interaction of IFN-α with its receptor activates multiple signaling pathways involved in innate immune responses against viral infection.
In humans, the IFN-α gene is located on chromosome 9, and the Type I interferon family includes 14 alpha isoforms along with beta, omega, epsilon, and kappa forms. IFN-α is primarily produced by plasmacytoid dendritic cells and plays a key role in antiviral defense and modulation of adaptive immunity.
Diseases associated with IFN-α dysfunction include Hepatitis C and Hepatitis.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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