Thermo Fisher Scientific Raptor Recombinant Rabbit Monoclonal Antibody (ARC1375)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1375

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1236-1335 of human Raptor (Q8N122) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Raptor,uniProtId:Q8N122-1,ncbiNodeId:9606,antigenRange:1236-1335,antigenLength:1335,antigenImageFileName:MA5-35742_Raptor_Q8N122-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35742_Raptor_Q8N122-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849642

Product Specific Information

Immunogen sequence: VRIFDPRMPE SVNVLQIVKG LTALDIHPQA DLIACGSVNQ FTAIYNSSGE LINNIKYYDG FMGQRVGAIS CLAFHPHWPH LAVGSNDYYI SVYSVEKRVR

Target Information

Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.