Thermo Fisher Scientific FH Monoclonal Antibody (OTI2A2), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:50–1:100

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The FH protein is an enzymatic component of the tricarboxylic acid (Krebs) cycle, catalyzing the conversion of fumarate to L-malate.
It exists in both cytosolic and mitochondrial forms, differing by translation start site. The mitochondrial form includes an N-terminal extension that is cleaved after import.
FH functions as a homotetramer and shares similarity with thermostable class II fumarases. Mutations in the FH gene can cause fumarase deficiency, leading to progressive encephalopathy.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.