Thermo Fisher Scientific SYNE1 Monoclonal Antibody (OTI1E10), TrueMAB
SYNE1 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 실험에 적합. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific SYNE1 Monoclonal Antibody (OTI1E10), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–285 of human SYNE1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended desalting product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882)
Target Information
SYNE1 (Nesprin-1) belongs to a family of type II integral membrane proteins characterized by multiple spectrin repeats, nuclear localization sequences, and a conserved C-terminal transmembrane domain.
These proteins are ubiquitously expressed, with tissue-specific isoforms generated through alternative splicing.
Nesprin-1 localizes to the nuclear membrane and is developmentally regulated in muscle cells, redistributing during myoblast differentiation.
Nesprins may function as “dystrophins of the nucleus,” maintaining nuclear organization and structural integrity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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