Thermo Fisher Scientific RXRA Monoclonal Antibody (3F5)
인간 RXRA 단백질을 인식하는 Mouse IgG2a monoclonal antibody. ELISA에 적합하며, 비결합형 액상 형태로 제공. Affinity chromatography로 정제되어 고순도. -20°C에서 보관, 연구용으로만 사용 가능.
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Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F5 |
| Immunogen | RXRA (NP_002948.1, 27 a.a. ~ 94 a.a) full-length recombinant protein with GST tag. MW of GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SMAAPSLHPS LGPGIGSPGQ LHSPISTLSS PINGMGPPFS VISSPMGPHS MSVPTTPTLG FSTGSPQL
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, regulates the transition of proliferating precursor cells (such as carcinoma and neuronal precursors) to postmitotic differentiated cells.
The Retinoid X Receptor (RXR) family (alpha, beta, gamma) preferentially binds 9-cis-RA and regulates gene transcription by forming heterodimers with RA receptors.
RAs may play a therapeutic role in cervical cancer and are known to be key regulators of neuronal development, synaptic plasticity, and learning and memory behaviors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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