Thermo Fisher Scientific RXRA Monoclonal Antibody (3F5)
Thermo Fisher Scientific의 RXRA Monoclonal Antibody (3F5)는 인간 RXRA 단백질을 인식하는 Mouse IgG2a 단일클론 항체입니다. Western blot 및 ELISA에 적합하며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3F5 |
| Immunogen | RXRA (NP_002948.1, 27 a.a. approximately 94 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SMAAPSLHPS LGPGIGSPGQ LHSPISTLSS PINGMGPPFS VISSPMGPHS MSVPTTPTLG FSTGSPQL
Target Information
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells.
The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors.
RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development, and increasing evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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