Thermo Fisher Scientific RXRA Monoclonal Antibody (3F5)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
SMAAPSLHPS LGPGIGSPGQ LHSPISTLSS PINGMGPPFS VISSPMGPHS MSVPTTPTLG FSTGSPQL

Target Information

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells.
The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors.
RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development, and increasing evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.