Thermo Fisher Scientific RXRA Monoclonal Antibody (4B5)
RXRA 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 4B5). Western blot, ELISA, Immunoprecipitation에 사용 가능. 인간 시료 반응성. 액상형, PBS buffer, 무보존제, -20°C 보관. 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4B5 |
| Immunogen | RXRA (AAH07925, 1 a.a. to ~165 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MLGSWPARTF HPGACVSRRP SAPWKHTASG KDSPDLRFSE HGVSQEFWAG GLVAVLEMTP SPSPWGTQEG PAGMCSLWVV GWCPCRGAGV RDLVLVHAGV WCKHVCAVQR DACGESRTPA PPRKGGAVTS VLCLFLIKTF PLFSYKFASC KQVHKDPPLV KSGFE
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, regulates the transition of proliferating precursor cells to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family—RXR alpha, beta, and gamma—preferentially bind 9-cis RA and regulate gene transcription by forming heterodimers with RA receptor family members. RAs may play a therapeutic role in cervical cancer and are key regulators in neuronal development, synaptic plasticity, and learning and memory behaviors.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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