Thermo Fisher Scientific GMEB2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GMEB2. Recombinant protein control fragment (Product #RP-89310). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GMEB2,uniProtId:Q9UKD1-1,ncbiNodeId:9606,antigenRange:394-519,antigenLength:530,antigenImageFileName:PA5-52678_GMEB2_Q9UKD1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52678_GMEB2_Q9UKD1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642068

Product Specific Information

Immunogen sequence: TSVPLGKVVS TLPSTVLGKG SLQAPPASSP ASPLLGGYTV LASSGSTYPS TVEIHPDASS LTVLSTAAVQ DGSTVFKVVS PLQLLTLPGL GPTLQNVAQA SPGSSTIVTV PAGAAPGPEE HTATIE

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.

Target Information

The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB40, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Single nucleotide polymorphisms near ZBTB40 have been linked to differences in bone mineral density of the hip and lumbar spine, and had a significant association with low-trauma fractures suggesting that ZBTB40 may be involved in bone development and formation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.