Thermo Fisher Scientific Atypical Chemokine Receptor D6 Polyclonal Antibody, FITC
Atypical Chemokine Receptor D6 단백질을 인식하는 FITC 결합 토끼 폴리클로날 항체. Western blot, ELISA, IP에 적합하며 인간, 생쥐, 랫트 시료에 반응. 형광 분석용으로 498/517 nm 파장에서 검출 가능.
- 카탈로그번호
- ACRD6H-FITC
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 200–300 on ACRD6 protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a beta chemokine receptor, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for recruiting effector immune cells to inflammation sites. The receptor is expressed in various tissues and hemopoietic cells. Its expression in lymphatic endothelial cells and vascular tumors suggests a role in chemokine-driven leukocyte recirculation and vascular tumor development. It binds many beta-chemokine family members, though its specific function remains unclear. The gene is mapped to chromosome 3p21.3, within a cluster of chemokine receptor genes.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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