Thermo Fisher Scientific LIMK1 Monoclonal Antibody (OTI6A7), TrueMAB
LIMK1 단백질을 인식하는 Mouse monoclonal antibody로, WB, ICC/IF, Flow Cytometry에 적합합니다. Human 시료에 반응하며, Lyophilized 형태로 제공됩니다. 고순도의 Affinity chromatography 정제 제품으로 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A7 |
| Immunogen | Full length human recombinant protein of human LIMK1 produced in HEK293 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIMK1 is a serine/threonine kinase involved in the regulation of actin cytoskeletal dynamics through phosphorylation of cofilin. It plays a role in brain development and is characterized by conserved LIM domains containing two zinc fingers that mediate protein-protein interactions. LIMK1 and LIMK2 form a subfamily with two N-terminal LIM motifs and a C-terminal kinase domain. LIMK1 hemizygosity has been linked to cognitive impairments in Williams syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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