Thermo Fisher Scientific IL9R Monoclonal Antibody (33423)
인간 IL9 수용체를 인식하는 Mouse IgG1 단클론 항체로, WB, ELISA, Neutralization, Inhibition Assay에 사용 가능. 고순도 Protein A 정제, 액상 형태, 0.5 mg/mL 농도. 연구용으로 IL9 관련 신호전달 연구에 적합.
- 카탈로그번호
- MA124800
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| ELISA | 0.5–1 µg/mL |
| Neutralization (Neu) | 2–4 µg/mL |
| Inhibition Assays (IA) | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 33423.111 |
| Immunogen | Purified recombinant human soluble IL-9 receptor, expressed in Sf21 insect cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_794656 |
Product Specific Information
The Neutralization Dose50 (ND50) for anti-human IL9R is approximately 2–4 µg/mL in the presence of 2 ng/mL of recombinant human IL9 using human MO7e cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG.
The interleukin 9 receptor (IL9R) is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively.
A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in various hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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