Thermo Fisher Scientific MAGEA11 Polyclonal Antibody

Thermo Fisher Scientific MAGEA11 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Recommended positive controls: A431, H1299
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

MAGEA11 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50–80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls.
MAGEA genes are expressed at a high level in a number of tumors of various histologic types and are silent in normal tissues except testis and placenta. The MAGEA genes are clustered on chromosome Xq28 and may be implicated in some hereditary disorders, such as dyskeratosis congenita.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.