Thermo Fisher Scientific FASN Polyclonal Antibody
Thermo Fisher Scientific의 FASN Polyclonal Antibody는 인간 및 생쥐 반응성을 가진 Rabbit IgG 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 지방산 합성 효소(FASN) 연구에 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 401–694 of Fatty Acid Synthase (Uniprot ID: P49327) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11154136 |
Product Specific Information
- Recommended positive controls: 293T, A431, HeLa, HepG2, Molt-4, Mouse liver
- Predicted reactivity: Mouse (84%), Rat (85%), Pig (80%), Bovine (81%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
Fatty acid synthase (FASN) is a multifunctional enzyme that catalyzes the synthesis of palmitate from acetyl-CoA and malonyl-CoA in the presence of NADPH, producing long-chain saturated fatty acids.
In certain cancer cell lines, FASN has been found fused with estrogen receptor-alpha (ER-alpha), where the N-terminus of FAS joins in-frame with the C-terminus of ER-alpha.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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