Thermo Fisher Scientific HPD Monoclonal Antibody (D2)
HPD 단백질을 인식하는 D2 클론의 마우스 모노클로날 항체로, Western blot, IHC, ICC/IF 등에 사용 가능. Human 및 Pig 반응성. Protein A/G로 정제된 액상 형태이며 1 mg/mL 농도. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D2 |
| Immunogen | Recombinant Human HPD protein (Thr2–Met393, Accession #P32754) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093356 |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity. Recently, a serine protease called Omi/HtrA2 has been identified, which is released from mitochondria upon induction of apoptosis. Omi binds to IAP and, like Smac/DIABLO, contains a conserved IAP-binding motif (AVPS) at its N terminus. Deregulated expression of Omi in the cytoplasm induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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