Thermo Fisher Scientific HPD Monoclonal Antibody (D1)
HPD 단백질을 인식하는 D1 클론의 마우스 모노클로날 항체. Western blot, IHC(P), ICC/IF에 사용 가능. 인간 및 돼지 시료 반응성. Protein A/G 정제, 1 mg/mL 농도 액상 형태. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D1 |
| Immunogen | Recombinant Human HPD protein, Thr2–Met393 (Accession #P32754) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093352 |
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif essential for their anti-apoptotic activity. A mitochondrial serine protease, Omi/HtrA2, binds to IAPs and is released upon apoptotic induction. The mature Omi protein contains a conserved IAP-binding motif (AVPS) at its N terminus. Deregulated expression of Omi in the cytoplasm induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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