Thermo Fisher Scientific MSRA Monoclonal Antibody (C6)
MSRA 단백질을 인식하는 Thermo Fisher Scientific의 C6 모노클론 항체. 인간, 돼지, 쥐에 반응하며 Western blot 및 IHC에 적합. 고순도 Protein A/G 정제, 액상 형태, 안정적인 장기 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.01–2 µg/mL
- Publications: [References available]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–20 µg/mL
- Publications: [References available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C6 |
| Immunogen | Recombinant Human MSRA protein, Ala27–Lys235 (Accession #Q9UJ68) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093365 |
Target Information
Methionine sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to methionine (Met).
The catalytic activity of MsrA depends on bound metal and cofactors, requiring reducing equivalents from either DTT or a thioredoxin-regenerating system.
MsrA plays an essential role in protecting cells against oxidative damage.
Substrates include calmodulin, HIV protease, and a 1-proteinase-inhibitor.
Recent studies indicate a connection between MsrA and Alzheimer’s disease in mammals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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