Thermo Fisher Scientific PTPRE Monoclonal Antibody (OTI2C11), TrueMAB
Human PTPRE 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. Lyophilized 형태로 제공되며, PBS 및 trehalose buffer에 보관합니다. 연구용으로 세포 신호전달 및 PTP 관련 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | - |
| Flow Cytometry (Flow) | 1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C11 |
| Immunogen | Full length human recombinant protein of human PTPRE produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The PTPRE gene encodes a member of the protein tyrosine phosphatase family, which regulates cellular processes such as growth, differentiation, mitotic cycle, and oncogenic transformation.
Two splice variants exist:
- A receptor-type PTP with a short extracellular domain, single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- A nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Mouse studies suggest PTPRE regulates RAS-related signaling, cytokine-induced SATA signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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