Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI4C1), TrueMAB
인간 LIPG 단백질에 특이적인 단클론 항체로 다양한 면역분석(WB, IHC, ICC, Flow, IP)에 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로 HDL 대사 및 지질 생리 연구에 적합.
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Thermo Fisher Scientific LIPG Monoclonal Antibody (OTI4C1), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4C1 |
| Immunogen | Full length human recombinant protein of human LIPG produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
LIPG (Lipase G, Endothelial type) is an endothelial lipase and a member of the lipoprotein lipase gene family. It is synthesized by endothelial cells and functions locally, playing a role in modulating lipoprotein metabolism.
Overexpression of LIPG reduces HDL cholesterol levels, while deficiency elevates HDL levels in animals. LIPG exhibits phospholipase activity and is involved in lipid metabolism and vascular biology. It belongs to the TG lipase family, characterized by a lid region that confers substrate specificity.
LIPG acts as a carboxyl esterase, hydrolyzing high-density lipoproteins, emulsifying triglycerides, and aiding in dietary fat digestion. It can also bind to heparin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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