Thermo Fisher Scientific SUFU Polyclonal Antibody
SUFU 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체로, WB, IHC, ICC, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며 PBS 기반 용액 형태로 제공됩니다. Hedgehog 신호전달 연구용으로 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 325–484 of human SUFU (NP_0572532) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.39 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806667 |
Product Specific Information
- Immunogen sequence:
PPINPQRQNG LAHDRAPSRK DSLESDSSTA IIPHELIRTR QLESVHLKFN QESGALIPLC LRGRLLHGRH FTYKSITGDM AITFVSTGVE GAFATEEHPY AAHGPWLQIL LTEEFVEKML EDLEDLTSPE EFKLPKEYSW PEKKLKVSIL PDVVFDSPLH - Positive Samples: Mouse testis, Rat kidney
- Cellular Location: Cytoplasm, Nucleus
Target Information
The Hedgehog signaling pathway plays an important role in early human development. It regulates pattern formation and cellular proliferation during development.
This gene encodes a negative regulator of the Hedgehog signaling pathway. Defects in this gene are associated with medulloblastoma. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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