Thermo Fisher Scientific Rhotekin Polyclonal Antibody
Rhotekin 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. Western blot, ICC/IF, ELISA 등에 사용 가능하며 Human, Mouse, Rat 반응성을 가집니다. 고순도 Affinity Chromatography로 정제된 액상 제품으로 연구용에 적합합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 254–513 of human RTKN (NP_0010150561) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.14 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806660 |
Product Specific Information
Immunogen sequence:
PLCMTQPTAS GTLRVQQAGE MQNWAQVHGV LKGTNLFCYR QPEDADTGEE PLLTIAVNKE TRVRAGELDQ ALGRPFTLSI SNQYGDDEVT HTLQTESREA LQSWMEALWQ LFFDMSQWKQ CCDEIMKIET PAPRKPPQAL AKQGSLYHEM AIEPLDDIAA VTDILTQREG ARLETPPPWL AMFTDQPALP NPCSPASVAP APDWTHPLPW GRPRTFSLDA VPPDHSPRAR SVAPLPPQRS PRTRGLCSKG QPRTWLQSPV
Positive Samples: A-431, HepG2, MCF7
Target Information
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. It may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate cellular processes including cytokinesis, transcription, smooth muscle contraction, cell growth, and transformation. Dysregulation of Rho signal transduction is implicated in various cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-93182_Rhotekin_Q9BST9-1_Rabbit.svg)
(이미지: PA5-93182_Rhotekin_Q9BST9-1_Rabbit_PDP.jpeg)
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