Thermo Fisher Scientific STK38L Polyclonal Antibody
STK38L 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat에서 반응하며, 세포질 및 세포막 위치 단백질 검출에 적합. 친화 크로마토그래피로 정제된 액상 항체로 -20°C에서 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 165–464 of human STK38L (NP_055815.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.86 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913931 |
Product Specific Information
Positive test controls include:
- HeLa
- Mouse small intestine
- Mouse brain
- Rat stomach
- Rat brain
The target is usually found in the following locations:
- Cytoplasm
- Membrane
- Cytoskeleton
Immunogen sequence:
LIMEFLPGGD MMTLLMKKDT LTEEETQFYI SETVLAIDAI HQLGFIHRDI KPDNLLLDAK GHVKLSDFGL CTGLKKAHRT EFYRNLTHNP PSDFSFQNMN SKRKAETWKK NRRQLAYSTV GTPDYIAPEV FMQTGYNKLC DWWSLGVIMY EMLIGYPPFC SETPQETYRK VMNWKETLVF PPEVPISEKA KDLILRFCID SENRIGNSGV EEIKGHPFFE GVDWEHIRER PAAIPIEIKS IDDTSNFDDF PESDILQPVP NTTEPDYKSK DWVFLNYTYK RFEGLTQRGS IPTYMKAGKL
Target Information
STK38L (also known as NDR2) or Nuclear Dbf2-related protein is a serine/threonine kinase in the AGC kinase family.
It acts as a novel pro-apoptotic kinase activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.
STK38L is involved in regulating structural processes in differentiating and mature neuronal cells, with highest expression in the thymus.
It contains 12 protein kinase catalytic subdomains and a potential bipartite nuclear localization signal.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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