Thermo Fisher Scientific Chromogranin A Polyclonal Antibody
Chromogranin A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 사용 가능. 인간 및 마우스 반응성, 고순도 항원 친화 크로마토그래피 정제. 신경내분비 종양 마커 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Chromogranin A (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735659 |
Product Specific Information
- Positive Control: SH-SY-5Y conditioned medium
- Predicted Reactivity: Rhesus Monkey (89%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins.
It is found in secretory vesicles of neurons and endocrine cells.
CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin.
These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system.
CHGA is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors.
Coexpression of Chromogranin A and neuron-specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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