Thermo Fisher Scientific IL-2 Monoclonal Antibody (MQ1-17H12)
IL-2 단일클론 항체 MQ1-17H12는 인간 및 생쥐 IL-2에 반응하며, IHC 및 Flow Cytometry에 적합합니다. Rat IgG2a 형식의 단일클론 항체로, Protein A로 정제되어 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific IL-2 Monoclonal Antibody (MQ1-17H12)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Flow Cytometry (Flow) | 0.5–5 µg/10^6 cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MQ1-17H12 |
| Immunogen | Recombinant protein of human IL-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Tosil
- Cellular location: Secreted
Target Information
Interleukin 2 (IL-2) is an immunomodulatory cytokine important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL-4 and IL-7.
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for precise gene expression.
Disruption of an IL-2–like gene in mice leads to an ulcerative colitis–like disease, indicating its essential role in immune response to antigenic stimuli.
Usage Restrictions
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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