Thermo Fisher Scientific GRIP1 Polyclonal Antibody
Human GRIP1 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 핵 수용체 코액티베이터 연구용으로 적합.
- 판매단위
- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GRIP1. Recombinant protein control fragment (Product #RP-97784) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790595 |
Product Specific Information
Immunogen sequence:
DSWDGSAIDT SYGTEGTSFQ ASGYNFNTYD WRSPKQRGSL SPVTKPRSQT YPDVGLSYED WDRSTAS
Target Information
Steroid, thyroid hormones, and retinoic acid regulate gene expression via intracellular receptor transcription factors of the ligand-dependent nuclear receptor superfamily. Coactivators and corepressors modulate transcription activity of these receptors.
Glucocorticoid receptor interacting protein-1 (GRIP1), also known as Transcription Intermediary Factor 2 (TIF2), is a transcriptional coactivator related to SRC-1 and AIB-1. GRIP1 interacts with and enhances transcriptional activity of retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and peroxisome proliferator activated receptors.
GRIP1 contains multiple LXXLL/LLXXL motifs critical for receptor-coactivator interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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