Thermo Fisher Scientific Phospho-TAOK2 (Ser181) Polyclonal Antibody
TAOK2 단백질의 Ser181 인산화 형태를 특이적으로 검출하는 폴리클로날 항체. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 사람, 생쥐, 랫트 반응성. 고순도 정제 및 안정한 PBS/glycerol 저장용액 제공.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TAO2 around the phosphorylation site of Ser181 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899286 |
Product Specific Information
This antibody detects endogenous levels of TAO2 only when phosphorylated at Ser181.
Target Information
TAOK2 (TAO1) is a serine/threonine kinase that may regulate the stress-responsive p38 MAP kinase pathway. In vitro, TAO2 activates MAP/ERK kinases (MEK) 3, 4, and 6 toward their substrates p38 MAP kinase and JNK/SAPK. Research indicates that TAO kinases play an essential role in signaling from physiological agonists to the stress-responsive p38 MAPK pathway. Autophosphorylation of TAO may contribute to its activation mechanism, and Ser181 is located within the MEK binding domain of TAO.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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