Thermo Fisher Scientific Synip Polyclonal Antibody
Synip 단백질(STXBP4)을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 비인간 영장류 반응성. 액상 형태, 1 mg/mL 농도, 친화 크로마토그래피로 정제. 연구용으로만 사용.
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Thermo Fisher Scientific Synip Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human STXBP4 (Accession Q6ZWJ1), corresponding to amino acid residues S442–L492 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852248 |
Product Specific Information
Antibody detects endogenous levels of total STXBP4.
Target Information
STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane.
It inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by binding STX4A and preventing the interaction between STX4A and VAMP2.
Insulin stimulation disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane.
STXBP4 may also play a role in regulating insulin release by pancreatic beta cells after glucose stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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