Thermo Fisher Scientific C11orf30 Polyclonal Antibody
인간 EMSY 단백질을 인식하는 C11orf30 폴리클로날 항체로, Western blot에 적합합니다. 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관됩니다. DNA 수리 관련 연구 및 BRCA2 상호작용 분석에 활용됩니다.
- 카탈로그번호
- PA5102867
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific C11orf30 Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EMSY (Accession Q7Z589), corresponding to amino acid residues Q414–Q464 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852251 |
Product Specific Information
Antibody detects endogenous levels of total C11orf30.
Target Information
EMSY is a regulator capable of repressing transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies chromatin. Its interaction with BRCA2 suggests it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex, it may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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