Thermo Fisher Scientific ASIP Polyclonal Antibody
인간 ASIP 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 합성 펩타이드 항원을 기반으로 제작되었으며, 액상 형태로 제공됩니다. PBS(glycerol 포함) 완충액에 보관하며, -20°C에서 안정적으로 저장 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ASIP (Accession P42127), corresponding to amino acid residues K81–N131 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852245 |
Product Specific Information
Antibody detects endogenous levels of total ASIP.
Target Information
In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may:
- Affect the quality of hair pigmentation
- Act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone
- Play a role in neuroendocrine aspects of melanocortin action
- Have a functional role in regulating lipid metabolism in adipocytes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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