Thermo Fisher Scientific CD16 Recombinant Rabbit Monoclonal Antibody (002)
Flow Cytometry에 적합한 Recombinant Rabbit Monoclonal CD16 항체. Mouse 시료 반응성. HEK293 세포 발현, Protein A 정제. 1 mg/mL 농도의 액상 형태로 제공되며, 보존제 무첨가. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 002 |
| Immunogen | Recombinant Mouse CD16/FCGR3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866656 |
Additional Formats
Target Information
CD16 encodes a receptor that recognizes the Fc portion of immunoglobulin G and is involved in the clearance of immune complexes from the circulation, as well as other functions such as cell-mediated cytotoxicity and enhancement of virus infections.
This gene, FCGR3A, shares a high degree of similarity with another nearby gene, FCGR3B, located on chromosome 1.
The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, while FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.
Mutations in this gene have been associated with Immunodeficiency 20 and have been linked to susceptibility to recurrent viral infections, systemic lupus erythematosus, and alloimmune neonatal neutropenia.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Diseases associated with FCGR3A include Immunodeficiency 20 and Herpes Zoster.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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