Thermo Fisher Scientific NCF2 Polyclonal Antibody
Human NCF2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ELISA, IP 등 다양한 응용에 적합. 보존제가 없는 액상 형태이며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
| Immunoprecipitation (IP) | 1–4 µL/mg of lysate |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NCF2/NCF-2/P67phox protein (Met1–Val526) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2788112 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human NCF2/NCF-2/P67phox.
Target Information
NCF2, NCF1, and a membrane-bound cytochrome b558 are required for activation of the latent NADPH oxidase, which is necessary for superoxide production.
Defects in NCF2 cause chronic granulomatous disease autosomal recessive cytochrome-b-positive type 2 (CGD2), a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill ingested microbes, leading to life-threatening bacterial and fungal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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