Thermo Fisher Scientific SERPINA1 Monoclonal Antibody (OTI11G2), TrueMAB
SERPINA1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, IP에 적합합니다. 인간 및 개에 반응하며, 고순도의 액상 형태로 제공됩니다. 연구용으로 단백질 발현 및 질병 관련 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunoprecipitation (IP) | 2 µg / 500 µL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11G2 |
| Immunogen | Full-length protein expressed in 293T cells transfected with human SERPINA1 expression vector |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Alpha-1-Antitrypsin (Alpha-1-AT) is synthesized in the liver and functions as an inhibitor of proteases such as trypsin, elastase, chymotrypsin, collagenase, leucocytic proteases, plasmin, and thrombin. Deficiency of Alpha-1-AT can lead to chronic obstructive lung disease (emphysema) and, less commonly, hepatic cirrhosis in infants and respiratory distress in newborns. Elevated Alpha-1-AT levels are observed as an acute phase response to tissue necrosis and inflammation, and are increased in conditions such as rheumatoid arthritis, bacterial infections, vasculitis, and carcinomatosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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