Thermo Fisher Scientific SMC2 Polyclonal Antibody
Human SMC2 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화됨. 항원 친화 크로마토그래피로 정제된 액상 제품이며, 4°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- A300057A
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific SMC2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 950–1000 of Human Structural Maintenance of Chromosomes 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are SMC (Structural Maintenance of Chromosome) family members forming a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during cell division.
hCAP-C/hCAP-E is a component of the condensin complex that interacts with phosphorylation of Histone H3, resulting in mitotic chromosome condensation.
The distribution patterns of the two heterodimeric complexes in the interphase nucleus indicate independent behavior of the complexes during the cell cycle, suggesting distinct roles in mitotic chromosome organization in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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