
Thermo Fisher Scientific SMC1 Polyclonal Antibody
SMC1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. Human과 Mouse 반응성, 항원 친화 크로마토그래피로 정제. 액상 형태로 4°C 보관.
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Thermo Fisher Scientific SMC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:2,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1175 and the C-terminus of Human Structural Maintenance of Chromosomes 1 (SMC1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Predicted to react with Rat and Bovine based on 100% sequence identity
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins are essential for nuclear events involving chromosome structure changes, such as mitotic organization, DNA recombination and repair, and transcriptional repression.
SMC1 and SMC3 form a heterodimeric complex necessary for metaphase progression and sister chromatid cohesion.
Mutations in the SMC1 gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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