Thermo Fisher Scientific DEDD Polyclonal Antibody
DEDD 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, 인간·생쥐·랫트 반응성. Western blot에 적합하며, 액상 형태로 PBS와 50% 글리세롤에 보관. 세포 사멸 관련 단백질 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DEDD (Accession O75618), corresponding to amino acid residues P138–K188 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899746 |
Product Specific Information
Antibody detects endogenous levels of total DEDD.
Target Information
DEDD encodes a protein containing a death effector domain (DED), a protein-protein interaction domain shared by adaptors, regulators, and executors of the programmed cell death pathway. Overexpression of this gene induces weak apoptosis. Upon stimulation, the protein translocates from cytoplasm to nucleus and colocalizes with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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