Thermo Fisher Scientific Phospho-JNK1/JNK2 (Thr183, Tyr185) Monoclonal Antibody (F.971.6)
JNK1/JNK2의 Thr183/Tyr185 인산화 상태를 검출하는 Rabbit monoclonal antibody. WB, IHC, IP에 적합하며 다양한 종(인간, 마우스, 랫, 효모 등)에 반응. 액상 형태로 −20°C 보관, 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 3 publications |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50 | - |
| Immunoprecipitation (IP) | 1:200 | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Rat, Yeast |
| Published Species | Fruit fly, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F.971.6 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pThr183/Tyr185 of human SAPK/JNK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 293 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 100 µg/mL BSA, 0.15M NaCl, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10981014 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
C-Jun N-terminal Kinase (JNK), also known as Mitogen-activated protein kinase (MAPK8), belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are serine/threonine protein kinases activated by various extracellular stimuli and mediate signal transduction from the cell surface to the nucleus.
JNK is involved in cellular processes such as proliferation, differentiation, transcription regulation, and development. JNK pathways are activated by stress and inflammatory signals, and expressed as ten isoforms due to differential mRNA splicing, with JNK1 and JNK2 being predominant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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