Thermo Fisher Scientific REV1 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 4–6 µg/mL

Product Specifications

Product Specific Information

• This antibody is expected to recognise both reported isoforms.
• Tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
• Preliminary analysis showed no signal in Western Blot.

Target Information

This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1.
The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions.
A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.
Two alternatively spliced transcript variants that encode different proteins have been found.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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