Thermo Fisher Scientific UBE2A/UBE2B Polyclonal Antibody
UBE2A/UBE2B 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot과 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 Affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human UBE2B (Accession P63146), corresponding to amino acid residues N94–I144 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816021 |
Product Specific Information
Antibody detects endogenous levels of total UBE2A/B.
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation.
Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s).
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family, required for post-replicative DNA damage repair.
Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, indicating that this enzyme is highly conserved in eukaryotic evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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