Thermo Fisher Scientific CD20 (MS4A1) Monoclonal Antibody (OTI4A4), Biotin, TrueMAB
인간 CD20(MS4A1)을 인식하는 Mouse IgG1 단클론 항체로, Biotin 결합형 TrueMAB 제품입니다. ELISA 및 Luminex 분석에 사용 가능하며, 고순도 친화 크로마토그래피 정제 및 안정적 PBS/BSA/glycerol 버퍼로 제공됩니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific CD20 (MS4A1) Monoclonal Antibody (OTI4A4), Biotin, TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:250–1:1,000 |
| Luminex | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A4 |
| Immunogen | Full length human recombinant protein of human MS4A1 produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
CD20 is a non-glycosylated surface phosphoprotein with a molecular weight of 33–37 kDa depending on phosphorylation. It is expressed on mature and most malignant B cells, a subset of T lymphocytes, and follicular dendritic cells. CD20 regulates transmembrane calcium conductance, cell cycle progression, and B-cell proliferation. It associates with lipid rafts and participates in BCR aggregation and signaling. CD20 remains on the cell surface after receptor ligation, making it a valuable target for antibody-mediated B-cell depletion. Dysfunctions in CD20 are linked to Ms4a1-related common variable immune deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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