Thermo Fisher Scientific BTK Monoclonal Antibody (OTI13E5), Biotin, TrueMAB
BTK 단백질을 인식하는 Biotin-conjugated mouse monoclonal antibody. ELISA 및 Luminex 분석에 적합하며, Human 시료에 반응. Affinity chromatography로 정제된 고순도 항체로 안정적인 PBS/BSA buffer에 보관.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| ELISA (ELISA) | 1:250–1:1,000 | |
| Luminex (LUM) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI13E5 |
| Immunogen | Full length human recombinant protein of human BTK produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It has been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9, which are critical molecules in innate and adaptive immunity. BTK also interacts with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting involvement in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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