Thermo Fisher Scientific NF-H Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:20,000-1:50000

View 3 publications 3 publications

Immunohistochemistry (IHC)

1:20,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:5,000

-

Immunohistochemistry (Frozen) (IHC (F))

1:2,000

-

Immunocytochemistry (ICC/IF)

1:5,000-1:10,000

View 2 publications 2 publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Bovine, Dog, Horse, Human, Mouse, Pig, Rat

Published species

Human, Mouse

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Native NF-H purified from bovine spinal cord.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1077155

Product Specific Information

This antibody reacts primarily with the phosphorylated axonal form of NF-H and shows some cross-reactivity with phosphorylated NF-M, which has similar phosphorylation sites to NF-H.

Target Information

Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-H has an important role in mature axons and is involved in amyotrophic lateral sclerosis (ALS).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.