Thermo Fisher Scientific Human APRIL Synthetic Peptide
Human APRIL 단백질의 세포외 도메인 근처 15개 아미노산으로 구성된 합성 펩타이드. APRIL 관련 항체의 차단 실험에 사용 가능. 인간 반응성, 액상 형태, PBS 버퍼에 보존. 연구용으로 면역반응 및 세포사멸 관련 연구에 적합.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the extracellular domain of human APRIL.
PEP-0101 can be used as a blocking peptide with polyclonal antibody PA5-19976.
Target Information
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified and designated APRIL (A PRoliferation-Inducing Ligand), TALL2 (TNF and ApoL-related Leukocyte-expressed Ligand 2), and TRDL 1a (TNF related death ligand 1a) in human and mouse.
Two receptors for APRIL were recently identified and designated TACI and BCMA.
APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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